The IIT Bombay campus is located at Powai, a suburb in north western Mumbai, between the Vihar and Powai lakes. The closest railway stops to IIT Mumbai on the Mumbai Suburban Railway are Kanjurmarg and Vikhroli, on the Central line. The four main entrances to the campus are the Main Gate, the Middle Gate (now closed for security reasons), the Y-Point Gate (also called the Market Gate) and the Lake Side Gate. The Main Gate is the only one which is open 24 hours a day, while the Y-Point Gate is open only between 7 a.m. to 11 p.m.

 
A lawn in IIT BombayThe campus is divided into clusters of buildings. The academic area chiefly comprises the Main Building, various Departmental annexures and auditoria. All department annexures are connected by a corridor named Infinite Corridor. Beyond the Convocation Hall lies the hostels (with the exception of Hostel 10, which is abutting the departmental annexure). The hostels are numbered from 1 through 13, with Hostel 10 (under-graduate and post-graduate) and Hostel 11 (post-graduate) specially reserved for women. Tansa House is a housing complex exclusively for the single male project staff. It is the smallest hostel in IIT Bombay with 128 rooms. The Tulsi House is meant for married research scholars. Apart from these, few students also reside in Type -1 quarters, Vihar House, QIP quarters and DRDO building which are situated in the campus.